Labial melanotic macule An oral melanotic macule is a harmless dark spot found on the lip, most often the lower lip, or inside the mouth, either on the gums, inside the cheek, or on the roof of the mouth. An oral melanotic Differential diagnosis of an oral mucosal pigmented lesion: a case of essential melanosis What Caused These Multiple Hyperpigmented Macules of the Mouth? Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review