Metabolic functions of the liver Deranged Physiology Disruption in glutathione metabolism and altered energy production in the liver and kidney after ischemic acute kidney injury in mice Scientific Reports Changes in Glutathione Content in Liver Diseases: An Update GCLC, the rate limiting enzyme in glutathione synthesis, promotes liver Download Scientific Diagram What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it