Initial clinical appearance with melanotic macules located on lower Download Scientific Diagram Pigmented Oral Lesions: Clues to Identifying the Potentially Malignant Consultant360 What Caused These Multiple Hyperpigmented Macules of the Mouth? 56M with an asymptomatic, darkly pigmented lesion on the attached gingiva of the maxilla, an irregularly shaped macule with varied pigmentation, including shades of black, brown, and gray. Brendan Gallagher, DDS Is focal melanotic lesion potentially malignant? A case report ScienceDirect