Modelling changes in glutathione homeostasis as a function of quinone redox metabolism Scientific Reports StructureActivity Correlation between Natural Glutathione Peroxidase (GPx) and Mimics: A Biomimetic Concept for the Design and Synthesis of More Efficient GPx Mimics Mugesh 2001 Chemistry A European Journal Wiley Online Library GLUTATHIONEtrying to learn more about it ** **The Methylation Cycle: ** After the methyl group gets transferred from L Methylfolate to the enzyme MTRR it is attached to "naked" B12 and this produces TJ. Glutathione peroxidase is an important enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. As a component of the glutathione cycle, it protects the liver from reactive oxygen metabolites. Selenocysteine Fig. 4.